What is the Tributyl(vinyl)tin?

Tributyl(vinyl)tin is Clear colorless to pale yellow liquid, while it's Molecular Formula is C14H30Sn. Clear colorless to pale yellow liquid Tributyl(vinyl)tin is used as a reagent in the palladium catalyzed synthesis of allyl and benzyl ethers. It is also a vinyl nucleophile for bromoacetylene and bromoaromatics.

What is the CAS number for Tributyl(vinyl)tin?

The CAS number of Tributyl(vinyl)tin is 7486-35-3.

What is Tributyl(vinyl)tin (7486-35-3) used for?

Tributyl(vinyl)tin, also known as tributylvinylstannane or vinyltributyltin, is an organotin compound used as a reagent in palladium-catalyzed coupling reactions, such as the Stille coupling, to introduce vinyl groups into organic molecules. It serves as a key intermediate in synthetic chemistry, particularly in the construction of complex structures like anthramycin derivatives, where it facilitates the attachment of functional side chains. Its reactivity with vinyl triflates under catalytic conditions makes it valuable for efficient and selective bond formation in pharmaceutical and materials synthesis.InChI:InChI=1/3C4H9.C2H3.Sn/c3*1-3-4-2;1-2;/h3*1,3-4H2,2H3;1H,2H2;/rC14H30Sn/c1-5-9-12-15(8-4,13-10-6-2)14-11-7-3/h8H,4-7,9-14H2,1-3H3

What is the Tributyl(vinyl)tin?

Tributyl(vinyl)tin is Clear colorless to pale yellow liquid, while it's Molecular Formula is C14H30Sn. Clear colorless to pale yellow liquid Tributyl(vinyl)tin is used as a reagent in the palladium catalyzed synthesis of allyl and benzyl ethers. It is also a vinyl nucleophile for bromoacetylene and bromoaromatics.

What is the CAS number for Tributyl(vinyl)tin?

The CAS number of Tributyl(vinyl)tin is 7486-35-3.

What is Tributyl(vinyl)tin (7486-35-3) used for?

Tributyl(vinyl)tin, also known as tributylvinylstannane or vinyltributyltin, is an organotin compound used as a reagent in palladium-catalyzed coupling reactions, such as the Stille coupling, to introduce vinyl groups into organic molecules. It serves as a key intermediate in synthetic chemistry, particularly in the construction of complex structures like anthramycin derivatives, where it facilitates the attachment of functional side chains. Its reactivity with vinyl triflates under catalytic conditions makes it valuable for efficient and selective bond formation in pharmaceutical and materials synthesis.InChI:InChI=1/3C4H9.C2H3.Sn/c3*1-3-4-2;1-2;/h3*1,3-4H2,2H3;1H,2H2;/rC14H30Sn/c1-5-9-12-15(8-4,13-10-6-2)14-11-7-3/h8H,4-7,9-14H2,1-3H3

Your Location:Home > Pharmaceutical > Tributyl(vinyl)tin

Product classification

Tributyl(vinyl)tin

Name:Tributyl(vinyl)tin
CAS:7486-35-3
Purity:99%

Inquiry

Details

Manufacturers supply cost-effective and customizable Tributyl(vinyl)tin 7486-35-3

Molecular Formula:C14H30Sn
Molecular Weight:317.102
Appearance/Colour:Clear colorless to pale yellow liquid
Vapor Pressure:0.0156mmHg at 25°C
Melting Point:<0 °C
Refractive Index:n20/D 1.478(lit.)
Boiling Point:104-106 °C (3.5 mmHg)
Flash Point:43 °C
PSA：0.00000
Density:1.085 g/mL at 25 °C(lit.)
LogP:5.56070

Tributyl(vinyl)tin(Cas 7486-35-3) Usage

Purification Methods

Fractionate the stannane under reduced pressure and taking the middle fraction to remove impurities such as (n-Bu)3SnCl. [Seyferth & Stone J Am Chem Soc 79 515 1957, Beilstein 16 III 1279.]

InChI:InChI=1/3C4H9.C2H3.Sn/c3*1-3-4-2;1-2;/h3*1,3-4H2,2H3;1H,2H2;/rC14H30Sn/c1-5-9-12-15(8-4,13-10-6-2)14-11-7-3/h8H,4-7,9-14H2,1-3H3

7486-35-3 Relevant articles

Ynamide Carbopalladation: A Flexible Route to Mono-, Bi- and Tricyclic Azacycles

Campbell, Craig D.,Greenaway, Rebecca L.,Holton, Oliver T.,Walker, P. Ross,Chapman, Helen A.,Russell, C. Adam,Carr, Greg,Thomson, Amber L.,Anderson, Edward A.

supporting information, p. 12627 - 12639 (2015/09/01)

Bromoenynamides represent precursors to ...

Stille coupling involving bulky groups feasible with gold cocatalyst

Delpozo, Juan,Carrasco, Desiree,Perez-Temprano, Monica H.,Garcia-Melchor, Max,Alvarez, Rosana,Casares, Juan A.,Espinet, Pablo

supporting information, p. 2189 - 2193 (2013/04/10)

Gold shuttle: Bulky groups, which will n...

A novel mode of access to polyfunctional organotin compounds and their reactivity in Stille cross-coupling reaction

Lamandé-Langle, Sandrine,Abarbri, Mohamed,Thibonnet, Jér?me,Duchêne, Alain

, p. 2368 - 2374 (2009/09/30)

Mono-, di-, tri- and tetra-functional or...

H NMR evidence for the formation of vinyllead triacetates. The reactions of vinylmercury, vinyltin, and vinylboronic acids with lead tetraacetate

Parkinson, Christopher J.,Stoermer, Martin J.

, p. 207 - 214 (2007/10/03)

Vinylmercury compounds, vinylboronic aci...

7486-35-3 Process route

: 101537-26-2
n-octyl ethynyl ether

: 111-87-5
octanol

: 929-62-4
n-octyl vinyl ether

: 7486-35-3
tri-n-butyl(vinyl)tin

: 813-19-4
bis(tri-n-butyltin)

: octyl 1-(tributylstannyl)vinyl ether

: octyl 2-(tributylstannyl)vinyl ether

Conditions

Conditions	Yield
With (Bu₃Sn)2Cu(CN)Li₂; In tetrahydrofuran; at -40 - 0 ℃; Product distribution; Mechanism; 1H-NMR spectra; different conditions, other cuprates and further acetylenic ether substrates;