1-(3-Chloropropoxy)-4-fluorobenzene
- Name:1-(3-Chloropropoxy)-4-fluorobenzene
- CAS:1716-42-3
- Purity:99%
Details
Reputable supplier selling 1-(3-Chloropropoxy)-4-fluorobenzene 1716-42-3 with stock
- Molecular Formula:C9H10ClFO
- Molecular Weight:188.629
- Appearance/Colour:clear yellowish to orange liquid
- Vapor Pressure:0.0148mmHg at 25°C
- Refractive Index:1.504-1.508
- Boiling Point:265.7 °C at 760 mmHg
- Flash Point:114.5 °C
- PSA：9.23000
- Density:1.164 g/cm3
- LogP:2.83340
1-(3-Chloropropoxy)-4-fluorobenzene(Cas 1716-42-3) Usage
InChI:InChI=1/C9H10ClFO/c10-6-1-7-12-9-4-2-8(11)3-5-9/h2-5H,1,6-7H2
1716-42-3 Relevant articles
Improved Potency of Indole-Based NorA Efflux Pump Inhibitors: From Serendipity toward Rational Design and Development
Buonerba, Federica,Lepri, Susan,Goracci, Laura,Schindler, Bryan D.,Seo, Susan M.,Kaatz, Glenn W.,Cruciani, Gabriele
, p. 517 - 523 (2017)
The NorA efflux pump is a potential drug...
Nickel-Catalyzed Dimerization and Alkylarylation of 1,3-Dienes with Alkyl Fluorides and Aryl Grignard Reagents
Iwasaki, Takanori,Min, Xin,Fukuoka, Asuka,Kuniyasu, Hitoshi,Kambe, Nobuaki
supporting information, p. 5550 - 5554 (2016/05/09)
In the presence of a nickel catalyst, 1,...
Copper-Catalyzed Regioselective Hydroalkylation of 1,3-Dienes with Alkyl Fluorides and Grignard Reagents
Iwasaki, Takanori,Shimizu, Ryohei,Imanishi, Reiko,Kuniyasu, Hitoshi,Kambe, Nobuaki
supporting information, p. 9347 - 9350 (2015/08/06)
Copper complexes generated in situ from ...
SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS
-
Page column 189, (2010/02/06)
This invention is directed to compounds ...
1716-42-3 Process route
-
-
371-41-5
4-Fluorophenol
-
-
109-70-6
1.3-chlorobromopropane
-
-
1716-42-3
1-(3-chloropropoxy)-4-fluorobenzene
| Conditions | Yield |
|---|---|
|
With
potassium carbonate;
In
acetone;
for 24h;
Heating;
|
89% |
|
With
potassium carbonate;
In
ethanol;
for 6h;
Reflux;
|
71% |
|
With
sodium hydroxide;
for 6h;
Heating;
|
60% |
|
With
ethanol; sodium ethanolate;
|
-
-
371-41-5
4-Fluorophenol
-
-
142-28-9
1,3-Dichloropropane
-
-
1716-42-3
1-(3-chloropropoxy)-4-fluorobenzene
| Conditions | Yield |
|---|---|
|
4-Fluorophenol; 1,3-Dichloropropane;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 0 ℃;
for 48h;
Reflux;
In
N,N-dimethyl-formamide;
at 100 ℃;
for 40h;
|
67% |
|
With
sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
at 0 - 100 ℃;
for 40h;
|
67% |
1716-42-3 Upstream products
-
371-41-5
4-Fluorophenol
-
109-70-6
1.3-chlorobromopropane
-
142-28-9
1,3-Dichloropropane
1716-42-3 Downstream products
-
1549-77-5
4-(4-fluorophenoxy)butyric acid
-
111626-10-9
4-[Bis(4-fluorophenyl)methyl]-1-[3-(4-fluorophenoxy)propyl]piperidine
-
253443-45-7
2-[3-(4-fluorophenoxy)propyl]-1H-isoindole-1,3(2H)-dione
-
78059-64-0
<(fluoro-4' phenoxy)-3 propyl>-1 hydroxy-4β trans-decahydroquinoleine
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