EQUILENIN

  • Name: EQUILENIN
  • CAS: 517-09-9
  • Purity: 99%
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Details

Reliable factory customized supply EQUILENIN 517-09-9

  • Molecular Formula: C18H18 O2
  • Molecular Weight: 266.34
  • Vapor Pressure: 1.48E-09mmHg at 25°C 
  • Melting Point: 258-259° 
  • Refractive Index: 1.4800 (estimate) 
  • Boiling Point: 472.6°Cat760mmHg 
  • PKA: pKa 9.72 (H2O t=25.0±0.02 ) (Uncertain);9.75±0.06 (Uncertain) 
  • Flash Point: 200.9°C 
  • PSA： 37.30000 
  • Density: 1.242g/cm3 
  • LogP: 3.94440 

EQUILENIN(Cas 517-09-9) Usage

Purification Methods

Crystallise (+)-equilenin from EtOH (solubility is 0.63% at 18o, 2.5% at 78o), aqueous EtOH or *C6H6 (Norite) and dry it in a vacuum. It sublimes on melting and at 170-180o/0.01mm. The acetate crystallises from MeOH with m 165-167o and [ ] D +71o (c 1, CHCl3). [Bachmann et al. J Am Chem Soc 62 824 1940, Beilstein 8 III 1522, 1523, 1525, 8 IV 1420.]

InChI:InChI=1/C18H18O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h2-5,10,16,19H,6-9H2,1H3/t16-,18-/m0/s1

517-09-9 Relevant articles

Practical semisynthesis of equilenin and its derivatives

Yue, Tao,Li, Hong-Ping,Ding, Kai

supporting information, p. 4850 - 4853 (2016/10/07)

Equilenin 2 and its derivatives are impo...

6-Hydroxyequilenins as estrogenic agents

-

, (2008/06/13)

This invention provides estrogen recepto...

An effective approach to B-ring aromatization of equilin

Cao, Zhisong,Liehr, Joachim G.

, p. 145 - 155 (2007/10/03)

Epoxidation of equilin followed by rearr...

Treating cardiac disorders with Δ9(11)-dehydro-8-isoestrone

-

, (2008/06/13)

This invention relates to 8α-3-hydroxyes...

517-09-9 Process route

3-O-methylequilinine
3907-67-3

3-O-methylequilinine

equilenin
517-09-9

equilenin

Conditions
Conditions Yield
With boron tribromide; In dichloromethane; at 0 ℃; for 0.5h;
90%
With boron tribromide; In dichloromethane; at -30 - 0 ℃; for 3h;
83%
With hydrogenchloride; acetic acid;
(9R,10S,11S,13S,14S)-9,11-Dichloro-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-6H-cyclopenta[a]phenanthrene-3,17-dione

(9R,10S,11S,13S,14S)-9,11-Dichloro-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-6H-cyclopenta[a]phenanthrene-3,17-dione

equilenin
517-09-9

equilenin

Conditions
Conditions Yield
With lithium chloride; In N,N-dimethyl-formamide; Heating;

517-09-9 Upstream products

  • 474-86-2
    474-86-2

    equilin

  • 6030-91-7
    6030-91-7

    equilenin acetate

  • 3907-67-3
    3907-67-3

    3-O-methylequilinine

  • 1423-97-8
    1423-97-8

    17β-dihydroequilenin

517-09-9 Downstream products

  • 41761-49-3
    41761-49-3

    (13S )-3-amino-13-methyl-(13r ,14t )-11,12,13,14,15,16-hexahydro-cyclopenta[a ]phenanthren-17-one

  • 17659-99-3
    17659-99-3

    (+/-)-Z-Bisdehydrodoisynolic acid

  • 5684-12-8
    5684-12-8

    3-hydroxy-16.17-seco-estrapentaen-(A.B )-oic acid-(17)

  • 16680-48-1
    16680-48-1

    sodium sulfate equilenin

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